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Cabello, J., & Rafecas, M. (2012). Comparison of basis functions for 3D PET reconstruction using a Monte Carlo system matrix. Phys. Med. Biol., 57(7), 1759–1777.
Abstract: In emission tomography, iterative statistical methods are accepted as the reconstruction algorithms that achieve the best image quality. The accuracy of these methods relies partly on the quality of the system response matrix (SRM) that characterizes the scanner. The more physical phenomena included in the SRM, the higher the SRM quality, and therefore higher image quality is obtained from the reconstruction process. High-resolution small animal scanners contain as many as 10(3)-10(4) small crystal pairs, while the field of view (FOV) is divided into hundreds of thousands of small voxels. These two characteristics have a significant impact on the number of elements to be calculated in the SRM. Monte Carlo (MC) methods have gained popularity as a way of calculating the SRM, due to the increased accuracy achievable, at the cost of introducing some statistical noise and long simulation times. In the work presented here the SRM is calculated using MC methods exploiting the cylindrical symmetries of the scanner, significantly reducing the simulation time necessary to calculate a high statistical quality SRM and the storage space necessary. The use of cylindrical symmetries makes polar voxels a convenient basis function. Alternatively, spherically symmetric basis functions result in improved noise properties compared to cubic and polar basis functions. The quality of reconstructed images using polar voxels, spherically symmetric basis functions on a polar grid, cubic voxels and post-reconstruction filtered polar and cubic voxels is compared from a noise and spatial resolution perspective. This study demonstrates that polar voxels perform as well as cubic voxels, reducing the simulation time necessary to calculate the SRM and the disk space necessary to store it. Results showed that spherically symmetric functions outperform polar and cubic basis functions in terms of noise properties, at the cost of slightly degraded spatial resolution, larger SRM file size and longer reconstruction times. However, we demonstrate that post-reconstruction smoothing, usually applied in emission imaging to reduce the level of noise, can produce a spatial resolution degradation of similar to 50%, while spherically symmetric basis functions produce a degradation of only similar to 6%, compared to polar and cubic voxels, at the same noise level. Therefore, the image quality trade-off obtained with blobs is higher than that obtained with cubic or polar voxels.
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Blume, M., Navab, N., & Rafecas, M. (2012). Joint image and motion reconstruction for PET using a B-spline motion model. Phys. Med. Biol., 57(24), 22pp.
Abstract: We present a novel joint image and motion reconstruction method for PET. The method is based on gated data and reconstructs an image together with amotion function. The motion function can be used to transform the reconstructed image to any of the input gates. All available events (from all gates) are used in the reconstruction. The presented method uses a B-spline motion model, together with a novel motion regularization procedure that does not need a regularization parameter (which is usually extremely difficult to adjust). Several image and motion grid levels are used in order to reduce the reconstruction time. In a simulation study, the presented method is compared to a recently proposed joint reconstruction method. While the presented method provides comparable reconstruction quality, it is much easier to use since no regularization parameter has to be chosen. Furthermore, since the B-spline discretization of the motion function depends on fewer parameters than a displacement field, the presented method is considerably faster and consumes less memory than its counterpart. The method is also applied to clinical data, for which a novel purely data-driven gating approach is presented.
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Calle Cordon, A., Pavon Valderrama, M., & Ruiz Arriola, E. (2012). Charge independence, charge symmetry breaking in the S-wave nucleon-nucleon interaction, and renormalization. Phys. Rev. C, 85(2), 024002–13pp.
Abstract: We explore the interplay between renormalization, charge independence and charge symmetry breaking (CIB and CSB) in S-wave nucleon-nucleon scattering. The renormalizability requirement generates universality functions, that is, correlations between the low-energy scattering observables in the neutron-neutron, neutron-proton, and proton-proton systems. The universality functions only depend on the (known) form of the nucleon-nucleon potential at long distances and, in particular, they do not require any assumptions about short-range CIB and CSB effects. In addition, the inclusion of Coulomb effects is trivial for the particular case of proton-proton scattering, allowing us to relate strong and Coulomb scattering observables. Within this approach, and using a one-boson-exchange potential, the previous correlations are shown to be phenomenologically satisfied without the need to introduce further parameters.
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Garcia-Recio, C., Nieves, J., Salcedo, L. L., & Tolos, L. (2012). D- mesic atoms. Phys. Rev. C, 85(2), 025203–13pp.
Abstract: The anti-D meson self-energy is evaluated self-consistently, using unitarized coupled-channel theory, by computing the in-medium meson-baryon T matrix in the C = -1, S = 0 sector. The heavy pseudo-scalar and heavy vector mesons, (D) over bar and (D) over bar*, are treated on equal footing as required by heavy-quark spin symmetry. Results for energy levels and widths of (D) over bar (-) mesic atoms in C-12, Ca-40, Sn-118, and Pb-208 are presented. The spectrum contains states of atomic and of nuclear types for all nuclei. (D) over bar (0)-nucleus bound states are also obtained. We find that, after electromagnetic and nuclear cascade, these systems end up with the (D) over bar bound in the nucleus, either as a meson or as part of an exotic (D) over barN (pentaquark) loosely bound state.
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Dijon, A. et al, Gadea, A., & Huyuk, T. (2012). Discovery of a new isomeric state in Ni-68: Evidence for a highly deformed proton intruder state. Phys. Rev. C, 85(3), 031301–5pp.
Abstract: We report on the observation of a new isomeric state in Ni-68. We suggest that the newly observed state at 168(1) keV above the first 2(+) state is a pi(2p-2h) 0(+) state across the major Z = 28 shell gap. Comparison with theoretical calculations indicates a pure proton intruder configuration and the deduced low-lying structure of this key nucleus suggests a possible shape coexistence scenario involving a highly deformed state.
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