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Author |
Piriz, G.H.; Gonzalez-Sprinberg, G.A.; Ballester, F.; Vijande, J. |
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Title |
Dosimetry of Large Field Valencia applicators for Cobalt-60-based brachytherapy |
Type |
Journal Article |
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Year |
2024 |
Publication |
Medical Physics |
Abbreviated Journal  |
Med. Phys. |
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Volume |
51 |
Issue |
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Pages |
5094-5098 |
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Keywords |
dosimetry; Monte Carlo; skin brachytherapy; Valencia applicators |
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Abstract |
BackgroundNon-melanoma skin cancer is one of the most common types of cancer and one of the main approaches is brachytherapy. For small lesions, the treatment of this cancer with brachytherapy can be done with two commercial applicators, one of these is the Large Field Valencia Applicators (LFVA).PurposeThe aim of this study is to test the capabilities of the LFVA to use clinically 60Co sources instead of the 192Ir ones. This study was designed for the same dwell positions and weights for both sources.MethodsThe Penelope Monte Carlo code was used to evaluate dose distribution in a water phantom when a 60Co source is considered. The LFVA design and the optimized dwell weights reported for the case of 192Ir are maintained with the only exception of the dwell weight of the central position, that was increased. 2D dose distributions, field flatness, symmetry and the leakage dose distribution around the applicator were calculated.ResultsWhen comparing the dose distributions of both sources, field flatness and symmetry remain unchanged. The only evident difference is an increase of the penumbra regions for all depths when using the 60Co source. Regarding leakage, the maximum dose within the air volume surrounding the applicator is in the order of 20% of the prescription dose for the 60Co source, but it decreases to less than 5% at about 1 cm distance.ConclusionsFlatness and symmetry remains unaltered as compared with 192Ir sources, while an increase in leakage has been observed. This proves the feasibility of using the LFVA in a larger range of clinical applications. |
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Address |
[Piriz, Gustavo H.; Gonzalez-Sprinberg, Gabriel A.] Univ Republica, Fac Sci, Med Phys Unit, Montevideo, Uruguay, Email: ghpiriz@gmail.com |
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Wiley |
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English |
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ISSN |
0094-2405 |
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Conference |
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Notes |
WOS:001187737100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6011 |
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Author |
Albiol, F.; Corbi, A.; Albiol, A. |
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Title |
3D measurements in conventional X-ray imaging with RGB-D sensors |
Type |
Journal Article |
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Year |
2017 |
Publication |
Medical Engineering & Physics |
Abbreviated Journal |
Med. Eng. Phys. |
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Volume |
42 |
Issue |
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Pages |
73-79 |
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Keywords |
X-ray; Depth cameras; Epipolar geometry; 3D reconstruction; Movement tracking; Dense surface mapping |
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Abstract |
A method for deriving 3D internal information in conventional X-ray settings is presented. It is based on the combination of a pair of radiographs from a patient and it avoids the use of X-ray-opaque fiducials and external reference structures. To achieve this goal, we augment an ordinary X-ray device with a consumer RGB-D camera. The patient' s rotation around the craniocaudal axis is tracked relative to this camera thanks to the depth information provided and the application of a modern surface-mapping algorithm. The measured spatial information is then translated to the reference frame of the X-ray imaging system. By using the intrinsic parameters of the diagnostic equipment, epipolar geometry, and X-ray images of the patient at different angles, 3D internal positions can be obtained. Both the RGB-D and Xray instruments are first geometrically calibrated to find their joint spatial transformation. The proposed method is applied to three rotating phantoms. The first two consist of an anthropomorphic head and a torso, which are filled with spherical lead bearings at precise locations. The third one is made of simple foam and has metal needles of several known lengths embedded in it. The results show that it is possible to resolve anatomical positions and lengths with a millimetric level of precision. With the proposed approach, internal 3D reconstructed coordinates and distances can be provided to the physician. It also contributes to reducing the invasiveness of ordinary X-ray environments and can replace other types of clinical explorations that are mainly aimed at measuring or geometrically relating elements that are present inside the patient's body. |
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Address |
[Albiol, Francisco; Corbi, Alberto] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46003 Valencia, Spain, Email: alberto.corbi@ific.uv.es |
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Elsevier Sci Ltd |
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English |
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ISSN |
1350-4533 |
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Notes |
WOS:000398007100008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3043 |
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Author |
Aggarwal, N. et al; Figueroa, D.G. |
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Title |
Challenges and opportunities of gravitational-wave searches at MHz to GHz frequencies |
Type |
Journal Article |
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Year |
2021 |
Publication |
Living Reviews in Relativity |
Abbreviated Journal |
Living Rev. Relativ. |
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Volume |
24 |
Issue |
1 |
Pages |
4 - 74pp |
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Keywords |
Ultra-high-frequency gravitational waves; Cosmological gravitational waves; Gravitational wave detectors; Fundamental physics with gavitational waves |
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Abstract |
The first direct measurement of gravitational waves by the LIGO and Virgo collaborations has opened up new avenues to explore our Universe. This white paper outlines the challenges and gains expected in gravitational-wave searches at frequencies above the LIGO/Virgo band, with a particular focus on Ultra High-Frequency Gravitational Waves (UHF-GWs), covering the MHz to GHz range. The absence of known astrophysical sources in this frequency range provides a unique opportunity to discover physics beyond the Standard Model operating both in the early and late Universe, and we highlight some of the most promising gravitational sources. We review several detector concepts that have been proposed to take up this challenge, and compare their expected sensitivity with the signal strength predicted in various models. This report is the summary of the workshop “Challenges and opportunities of high-frequency gravitational wave detection” held at ICTP Trieste, Italy in October 2019, that set up the stage for the recently launched Ultra-High-Frequency Gravitational Wave (UHF-GW) initiative. |
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Address |
[Aggarwal, Nancy] Northwestern Univ, Dept Phys & Astron, Ctr Interdisciplinary Explorat & Res Astrophys CI, Ctr Fundamental Phys, Evanston, IL 60208 USA, Email: nancy.aggarwal@northwestern.edu; |
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Publisher |
Springer Int Publ Ag |
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English |
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ISSN |
2367-3613 |
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Notes |
WOS:000727359500002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5074 |
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Author |
Pujades, M.C.; Granero, D.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Papagiannis, P.; Siebert, F.A. |
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Title |
Air-kerma evaluation at the maze entrance of HDR brachytherapy facilities |
Type |
Journal Article |
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Year |
2014 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
34 |
Issue |
4 |
Pages |
741-753 |
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Keywords |
bunker; shielding; NCRP 151; brachytherapy; Monte Carlo |
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Abstract |
In the absence of procedures for evaluating the design of brachytherapy (BT) facilities for radiation protection purposes, the methodology used for external beam radiotherapy facilities is often adapted. The purpose of this study is to adapt the NCRP 151 methodology for estimating the air-kerma rate at the door in BT facilities. Such methodology was checked against Monte Carlo (MC) techniques using the code Geant4. Five different facility designs were studied for Ir-192 and Co-60 HDR applications to account for several different bunker layouts. For the estimation of the lead thickness needed at the door, the use of transmission data for the real spectra at the door instead of the ones emitted by Ir-192 and Co-60 will reduce the lead thickness by a factor of five for Ir-192 and ten for Co-60. This will significantly lighten the door and hence simplify construction and operating requirements for all bunkers. The adaptation proposed in this study to estimate the air-kerma rate at the door depends on the complexity of the maze: it provides good results for bunkers with a maze (i.e. similar to those used for linacs for which the NCRP 151 methodology was developed) but fails for less conventional designs. For those facilities, a specific Monte Carlo study is in order for reasons of safety and cost-effectiveness. |
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Address |
[Pujades, M. C.] Natl Ctr Dosimetry CND, Valencia, Spain, Email: mpuclau@gmail.com |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0952-4746 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000345895800005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2031 |
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Author |
Gimenez-Alventosa, V.; Vijande, J.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Transit dose comparisons for Co-60 and Ir-192 HDR sources |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
36 |
Issue |
4 |
Pages |
858-864 |
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Keywords |
Monte Carlo; dosimetry; HDR brachytherapy; transit dose |
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Abstract |
The goal of this study is to evaluate the ambient dose due to the transit of high dose rate (HDR) Co-60 sources along a transfer tube as compared to Ir-192 ones in a realistic clinical scenario. This goal is accomplished by evaluating air-kerma differences with Monte Carlo calculations using PENELOPE2011. Scatter from both the afterloader and the patient was not taken into account. Two sources, mHDR-v2 and Flexisource Co-60, (Elekta Brachytherapy, Veenendaal, the Netherlands) have been considered. These sources were simulated within a standard transfer tube located in an infinite air phantom. The movement of the source was included by displacing their positions along the connecting tube from z = – 75 cm to z = + 75 cm and combining them. Since modern afterloaders like Flexitron (Elekta) or Saginova (BEBIG GmbH) are able to use equally 192Ir and 60Co sources, it was assumed that both sources are displaced with equal speed. Typical HDR source activity content values were provided by the manufacturer. 2D distributions were obtained with type-A uncertainties (k = 2) less than 0.01%. From those, the air-kerma ratio Co-60/Ir-192 was evaluated weighted by their corresponding typical activities. It was found that it varies slowly with distance (less than 10% variation at 75 cm) but strongly in time due to the shorter half-life of the 192Ir (73.83 d). The maximum ratio is located close to the tube. It reaches a value of 0.57 when the typical activity of the sources at the time when they were installed by the vendor was used. Such ratio increases up to 1.28 at the end of the recommended working life (90 d) of the Ir-192 source. Co-60/Ir-192 air-kerma ratios are almost constant (0.51-0.57) in the vicinity of the source-tube with recent installed sources. Nevertheless, air-kerma ratios increase rapidly (1.15-1.29) whenever the Ir-192 is approaching the end of its life. In case of a medical event requiring the medical staff to access the treatment room, these ratios indicate that the dosimetric impact on the medical team will be lower, with a few exceptions, in the case of Co-60-based HDR brachytherapy as compared to Ir-192-based one when typical air-kerma strength values are considered. |
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Address |
[Gimenez-Alventosa, Vicent; Vijande, Javier; Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: javier.vijande@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
0952-4746 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000386436100002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2839 |
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Author |
Ibanez-Rosello, B.; Bautista-Ballesteros, J.A.; Candela-Juan, C.; Villaescusa, J.I.; Ballester, F.; Vijande, J.; Perez-Calatayud, J. |
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Title |
Evaluation of the shielding in a treatment room with an electronic brachytherapy unit |
Type |
Journal Article |
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Year |
2017 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
37 |
Issue |
2 |
Pages |
N5-N12 |
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Keywords |
Esteya; electronic brachytherapy; shielding; radiation protection |
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Abstract |
Esteya (R) (Elekta Brachytherapy, Veenendaal, The Netherlands) is an electronic brachytherapy (eBT) system based on a 69.5 kVp x-ray source and a set of collimators of 1 to 3 cm in diameter, used for treating non-melanoma skin cancer lesions. This study aims to estimate room shielding requirements for this unit. The non-primary (scattered and leakage) ambient dose equivalent rates were measured with a Berthold LB-133 monitor (Berthold Technologies, Bad Wildbad, Germany). The latter ranges from 17 mSv h(-1) at 0.25 m distance from the x-ray source to 0.1 mSv h(-1) at 2.5 m. The necessary room shielding was then estimated following US and some European guidelines. The room shielding for all barriers considered was below 2 mmPb. The dose to a companion who, exceptionally, would stay with the patient during all treatment was estimated to be below 1 mSv if a leaded apron is used. In conclusion, Esteya shielding requirements are minimal. |
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Address |
[Ibanez-Rosello, Blanca; Ignacio Villaescusa, Juan] La Fe Univ, Radioprotect Dept, E-46026 Valencia, Spain, Email: blanca.ibanez.rosello@gmail.com |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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ISSN |
0952-4746 |
ISBN |
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Conference |
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Notes |
WOS:000413778600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3344 |
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Author |
Garcia-Cases, F.; Perez-Calatayud, J.; Ballester, F.; Vijande, J.; Granero, D. |
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Title |
Peripheral dose around a mobile linac for intraoperative radiotherapy: radiation protection aspects |
Type |
Journal Article |
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Year |
2018 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
38 |
Issue |
4 |
Pages |
1393-1411 |
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Keywords |
Mobetron; mobile electron linear accelerator; radiotherapy intraoperative |
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Abstract |
The aim of this work is to analyse the scattered radiation produced by the mobile accelerator Mobetron 1000. To do so, detailed Monte Carlo simulations using two different codes, Penelope2008 and Geant4, were performed. Measurements were also done. To quantify the attenuation due to the internal structures, present in the accelerator head, on the scattered radiation produced, some of the main structural shielding in the Mobetron 1000 has been incorporated into the geometry simulation. Results are compared with measurements. Some discrepancies between the calculated and measured dose values were found. These differences can be traced back to the importance of the radiation component due to low energy scattered electrons. This encouraged us to perform additional calculations to separate the role played by this component. Ambient dose equivalent, H*(10), outside of the operating room (OR) has been evaluated using Geant4. H*(10) has been measured inside and outside the OR, being its values compatible with those reported in the literature once the low energy electron component is removed. With respect to the role played by neutrons, estimations of neutron H*(10) using Geant4 together with H*(10) measurements has been performed for the case of the 12 MeV electron beam. The values obtained agree with the experimental values existing in the literature, being much smaller than those registered in conventional accelerators. This study is a useful tool for the clinical user to investigate the radiation protection issues arising with the use of these accelerators in ORs without structural shielding. These results will also enable to better fix the maximum number of treatments that could be performed while insuring adequate radiological protection of workers and public in the hospital. |
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Address |
[Garcia-Cases, F.] Hosp Univ San Juan de Alicante, Serv Radiofis & Protecc Radiol, Alacant, Spain, Email: garcia_frad@gva.es |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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English |
Summary Language |
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Series Editor |
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ISSN |
0952-4746 |
ISBN |
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Conference |
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Notes |
WOS:000448769200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3784 |
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Author |
Verdu-Andres, S.; Amaldi, U.; Faus-Golfe, A. |
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Title |
CABOTO, a high-gradient linac for hadrontherapy |
Type |
Journal Article |
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Year |
2013 |
Publication |
Journal of Radiation Research |
Abbreviated Journal |
J. Radiat. Res. |
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Volume |
54 |
Issue |
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Pages |
155-161 |
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Keywords |
hadrontherapy; high-gradient linac; cyclinac; carbon ion therapy; multipainting |
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Abstract |
The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances. |
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Address |
[Verdu-Andres, Silvia; Amaldi, Ugo] Fdn Tera, I-28100 Novara, Italy, Email: sverdu@bnl.gov |
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Publisher |
Oxford Univ Press |
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English |
Summary Language |
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Abbreviated Series Title |
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Edition |
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ISSN |
0449-3060 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000321463900021 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1506 |
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Author |
Roman, F.L.; Abler, D.; Kanellopoulos, V.; Amoros, G.; Davies, J.; Dosanjh, M.; Jena, R.; Kirkby, N.; Peach, K.; Salt, J. |
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Title |
Hadron therapy information sharing prototype |
Type |
Journal Article |
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Year |
2013 |
Publication |
Journal of Radiation Research |
Abbreviated Journal |
J. Radiat. Res. |
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Volume |
54 |
Issue |
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Pages |
56-60 |
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Keywords |
hadron therapy; proton therapy; data federation; web portal; eHealth; cancer informatics |
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Abstract |
The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components. |
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Address |
[Roman, Faustin Laurentiu; Abler, Daniel; Kanellopoulos, Vassiliki; Dosanjh, Manjit] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: faustin.roman@medaustron.at |
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Publisher |
Oxford Univ Press |
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English |
Summary Language |
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ISSN |
0449-3060 |
ISBN |
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Conference |
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Notes |
WOS:000321463900008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1519 |
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Author |
Davesne, D.; Pastore, A.; Navarro, J. |
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Title |
Fitting (NLO)-L-3 pseudo-potentials through central plus tensor Landau parameters |
Type |
Journal Article |
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Year |
2014 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
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Volume |
41 |
Issue |
6 |
Pages |
065104 - 12pp |
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Keywords |
Landau parameters; (NLO)-L-3; phenomenological interactions; fitting methods |
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Abstract |
Landau parameters determined from phenomenological finite-range interactions are used to get an estimation of next-to-next-to-next-to-leading order ((NLO)-L-3) pseudo-potentials parameters. The parameter sets obtained in this way are shown to lead to consistent results concerning saturation properties. The uniqueness of this procedure is discussed, and an estimate of the error induced by the truncation at (NLO)-L-3 is given. |
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Address |
[Davesne, D.] Univ Lyon, F-69622 Lyon, France, Email: davesne@inpl.in2p3.fr |
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Publisher |
Iop Publishing Ltd |
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Language |
English |
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ISSN |
0954-3899 |
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Notes |
WOS:000338425100009 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1838 |
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