TY  - JOUR
AU  - Barrientos, L.
AU  - Borja-Lloret, M.
AU  - Casaña, J. V.
AU  - Dendooven, P.
AU  - Garcia Lopez, J. G.
AU  - Hueso-Gonzalez, F.
AU  - Jiméeez-Ramos, M. C.
AU  - Perez-Curbelo, J.
AU  - Ros, A.
AU  - Roser, J.
AU  - Senra, C.
AU  - Viegas, R.
AU  - Llosa, G.
PY  - 2024
DA  - 2024//
TI  - Gamma-ray sources imaging and test-beam results with MACACO III Compton camera
T2  - Phys. Medica
JO  - Physica Medica
SP  - 103199
EP  - 10pp
VL  - 117
PB  - Elsevier Sci Ltd
KW  - Hadron therapy
KW  - Compton camera
KW  - Scintillator crystals
KW  - Silicon photomultipliers
AB  - Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s.
SN  - 1120-1797
UR  - https://doi.org/10.1016/j.ejmp.2023.103199
DO  - 10.1016/j.ejmp.2023.103199
LA  - English
N1  - WOS:001145147400001
ID  - Barrientos_etal2024
ER  -