PT Journal AU DUNE Collaboration (Abud, AAea Antonova, M Barenboim, G Cervera-Villanueva, A De Romeri, V Fernandez Menendez, P Garcia-Peris, MA Izmaylov, A Martin-Albo, J Masud, M Mena, O Molina Bueno, L Novella, P Rubio, FC Sorel, M Ternes, CA Tortola, M Valle, JWF TI Design, construction and operation of the ProtoDUNE-SP Liquid Argon TPC SO Journal of Instrumentation JI J. Instrum. PY 2022 BP P01005 - 111pp VL 17 IS 1 DI 10.1088/1748-0221/17/01/P01005 LA English DE Noble liquid detectors (scintillation; ionization; double-phase); Photon detectors for UV; visible and IR photons (solid-state) (PIN diodes; APDs; Si-PMTs; G-APDs; CCDs; EBCCDs; EMCCDs; CMOS imagers; etc); Scintillators; scintillation and light emission processes (solid; gas and liquid scintillators); Time projection Chambers (TPC) AB The ProtoDUNE-SP detector is a single-phase liquid argon time projection chamber (LArTPC) that was constructed and operated in the CERN North Area at the end of the H4 beamline. This detector is a prototype for the first far detector module of the Deep Underground Neutrino Experiment (DUNE), which will be constructed at the Sandford Underground Research Facility (SURF) in Lead, South Dakota, U.S.A. The ProtoDUNE-SP detector incorporates full-size components as designed for DUNE and has an active volume of 7 x 6 x 7.2 m3. The H4 beam delivers incident particles with well-measured momenta and high-purity particle identification. ProtoDUNE-SP's successful operation between 2018 and 2020 demonstrates the effectiveness of the single-phase far detector design. This paper describes the design, construction, assembly and operation of the detector components. ER