PT Journal
AU Trbojevich, RA
   Fernandez, A
   Watanabe, F
   Mustafa, T
   Bryant, MS
TI Comparative study of silver nanoparticle permeation using Side-Bi-Side and Franz diffusion cells
SO Journal of Nanoparticle Research
JI J. Nanopart. Res.
PY 2016
BP 55 - 12pp
VL 18
IS 3
DI 10.1007/s11051-016-3363-8
LA English
DE Membranes; Silver nanoparticles; Diffusion cells; Food packaging; Permeation; Environmental and health effects
AB Better understanding the mechanisms of nanoparticle permeation through membranes and packaging polymers has important implications for the evaluation of drug transdermal uptake, in food safety and the environmental implications of nanotechnology. In this study, permeation of 21 nm diameter silver nanoparticles (AgNPs) was tested using Side-Bi-Side and Franz static diffusion cells through hydrophilic 0.1 and 0.05 lm pore diameter 125 μm thick synthetic cellulose membranes, and 16 and 120 μm thick low-density polyethylene (LDPE) films. Experiments performed with LDPE films discarded permeation of AgNPs or Ag ions over the investigated time-frame in both diffusion systems. But controlled release of AgNPs has been quantified using semipermeable hydrophilic membranes. The permeation followed a quasi-linear time-dependent model during the experimental time-frame, which represents surface reaction-limited permeation. Diffusive flux, diffusion coefficients, and membrane permeability were determined as a function of pore size and diffusion model. Concentration gradient and pore size were key to understand mass transfer phenomena in the diffusion systems.
ER