TY  - JOUR
AU  - Amaldi, U.
AU  - Bonomi, R.
AU  - Braccini, S.
AU  - Crescenti, M.
AU  - Degiovanni, A.
AU  - Garlasche, M.
AU  - Garonna, A.
AU  - Magrin, G.
AU  - Mellace, C.
AU  - Pearce, P.
AU  - Pitta, G.
AU  - Puggioni, P.
AU  - Rosso, E.
AU  - Verdu-Andres, S.
AU  - Wegner, R.
AU  - Weiss, M.
AU  - Zennaro, R.
PY  - 2010
DA  - 2010//
TI  - Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs
T2  - Nucl. Instrum. Methods Phys. Res. A
JO  - Nuclear Instruments & Methods in Physics Research A
SP  - 563
EP  - 577
VL  - 620
IS  - 2-3
PB  - Elsevier Science Bv
KW  - Medical accelerators
KW  - Linac
KW  - Cyclotron
KW  - Synchrotron
KW  - Cyclinac
KW  - Radiation oncology
KW  - Hadrontherapy
KW  - Particle therapy
KW  - Proton therapy
KW  - Carbon ion therapy
KW  - Dose delivery
AB  - Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and 'single room' proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs.
SN  - 0168-9002
UR  - https://doi.org/10.1016/j.nima.2010.03.130
DO  - 10.1016/j.nima.2010.03.130
LA  - English
N1  - ISI:000280601700058
ID  - Amaldi_etal2010
ER  -