TY  - JOUR
AU  - Hueso-Gonzalez, F.
AU  - Ballester, F.
AU  - Perez-Calatayud, J.
AU  - Siebert, F. A.
AU  - Vijande, J.
PY  - 2017
DA  - 2017//
TI  - Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent I-125 prostate brachytherapy
T2  - Brachytherapy
JO  - Brachytherapy
SP  - 616
EP  - 623
VL  - 16
IS  - 3
PB  - Elsevier Science Inc
KW  - Brachytherapy
KW  - Low-dose rate
KW  - Heterogeneities
KW  - Prostate
KW  - Calcifications
KW  - Dosimetry
AB  - PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 1251 seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. RESULTS: Dose volume histogram related parameters like prostate D-90, rectum D-2cc, or urethra D-10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. CONCLUSIONS: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
SN  - 1538-4721
UR  - https://doi.org/10.1016/j.brachy.2017.02.005
DO  - 10.1016/j.brachy.2017.02.005
LA  - English
N1  - WOS:000402231600019
ID  - Hueso-Gonzalez_etal2017
ER  -