TY  - JOUR
AU  - Hueso-Gonzalez, F.
AU  - Vijande, J.
AU  - Ballester, F.
AU  - Perez-Calatayud, J.
AU  - Siebert, F. A.
PY  - 2015
DA  - 2015//
TI  - A simple analytical method for heterogeneity corrections in low dose rate prostate brachytherapy
T2  - Phys. Med. Biol.
JO  - Physics in Medicine and Biology
SP  - 5455
EP  - 5469
VL  - 60
IS  - 14
PB  - Iop Publishing Ltd
KW  - brachytherapy
KW  - low dose rate
KW  - heterogeneities
KW  - prostate
KW  - calcifications
AB  - In low energy brachytherapy, the presence of tissue heterogeneities contributes significantly to the discrepancies observed between treatment plan and delivered dose. In this work, we present a simplified analytical dose calculation algorithm for heterogeneous tissue. We compare it with Monte Carlo computations and assess its suitability for integration in clinical treatment planning systems. The algorithm, named as RayStretch, is based on the classic equivalent path length method and TG-43 reference data. Analytical and Monte Carlo dose calculations using Penelope2008 are compared for a benchmark case: a prostate patient with calcifications. The results show a remarkable agreement between simulation and algorithm, the latter having, in addition, a high calculation speed. The proposed analytical model is compatible with clinical real-time treatment planning systems based on TG-43 consensus datasets for improving dose calculation and treatment quality in heterogeneous tissue. Moreover, the algorithm is applicable for any type of heterogeneities.
SN  - 0031-9155
UR  - https://doi.org/10.1088/0031-9155/60/14/5455
DO  - 10.1088/0031-9155/60/14/5455
LA  - English
N1  - WOS:000357620400009
ID  - Hueso-Gonzalez_etal2015
ER  -