PT Journal AU Blume, M Navab, N Rafecas, M TI Joint image and motion reconstruction for PET using a B-spline motion model SO Physics in Medicine and Biology JI Phys. Med. Biol. PY 2012 BP 22pp VL 57 IS 24 DI 10.1088/0031-9155/57/24/8249 LA English AB We present a novel joint image and motion reconstruction method for PET. The method is based on gated data and reconstructs an image together with amotion function. The motion function can be used to transform the reconstructed image to any of the input gates. All available events (from all gates) are used in the reconstruction. The presented method uses a B-spline motion model, together with a novel motion regularization procedure that does not need a regularization parameter (which is usually extremely difficult to adjust). Several image and motion grid levels are used in order to reduce the reconstruction time. In a simulation study, the presented method is compared to a recently proposed joint reconstruction method. While the presented method provides comparable reconstruction quality, it is much easier to use since no regularization parameter has to be chosen. Furthermore, since the B-spline discretization of the motion function depends on fewer parameters than a displacement field, the presented method is considerably faster and consumes less memory than its counterpart. The method is also applied to clinical data, for which a novel purely data-driven gating approach is presented. ER