@Article{Nacher_etal2024, author="Nacher, E. and Briz, J. A. and Nerio, A. N. and Perea, A. and Tavora, V. G. and Tengblad, O. and Ciemala, M. and Cieplicka-Orynczak, N. and Maj, A. and Mazurek, K. and Olko, P. and Zieblinski, M. and Borge, M. J. G.", title="Characterization of a novel proton-CT scanner based on Silicon and LaBr3(Ce) detectors", journal="European Physical Journal Plus", year="2024", publisher="Springer Heidelberg", volume="139", number="5", pages="404--9pp", abstract="Treatment planning systems at proton-therapy centres entirely use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body, as derived from X-ray images, suffer from important proton-range uncertainties. In order to reduce this uncertainty in range, one could use proton-CT images instead. The main goal of this work is to test the capabilities of a newly-developed proton-CT scanner, based on the use of a set of tracking detectors and a high energy resolution scintillator for the residual energy of the protons. Different custom-made phantoms were positioned at the field of view of the scanner and were irradiated with protons at the CCB proton-therapy center in Krakow. We measured with the phantoms at different angles and produced sinograms that were used to obtain reconstructed images by Filtered Back-Projection. The obtained images were used to determine the capabilities of our scanner in terms of spatial resolution and proton Relative Stopping Power (RSP) mapping and validate its use as proton-CT scanner. The results show that the scanner can produce medium-high quality images, with spatial resolution better than 2 mm in radiography, below 3 mm in tomography and resolving power in the RSP comparable to other state-of-the-art pCT scanners.", optnote="WOS:001218502700005", optnote="exported from refbase (https://references.ific.uv.es/refbase/show.php?record=6123), last updated on Thu, 23 May 2024 19:29:01 +0000", issn="2190-5444", doi="10.1140/epjp/s13360-024-05203-1", opturl="https://arxiv.org/abs/2307.04273", opturl="https://doi.org/10.1140/epjp/s13360-024-05203-1", language="English" }