@Article{Amaldi_etal2010, author="Amaldi, U. and Bonomi, R. and Braccini, S. and Crescenti, M. and Degiovanni, A. and Garlasche, M. and Garonna, A. and Magrin, G. and Mellace, C. and Pearce, P. and Pitta, G. and Puggioni, P. and Rosso, E. and Verdu-Andres, S. and Wegner, R. and Weiss, M. and Zennaro, R.", title="Accelerators for hadrontherapy: From Lawrence cyclotrons to linacs", journal="Nuclear Instruments {\&} Methods in Physics Research A", year="2010", publisher="Elsevier Science Bv", volume="620", number="2-3", pages="563--577", optkeywords="Medical accelerators; Linac; Cyclotron; Synchrotron; Cyclinac; Radiation oncology; Hadrontherapy; Particle therapy; Proton therapy; Carbon ion therapy; Dose delivery", abstract="Hadrontherapy with protons and carbon ions is a fast developing methodology in radiation oncology. The accelerators used and planned for this purpose are reviewed starting from the cyclotrons used in the thirties. As discussed in the first part of this paper, normal and superconducting cyclotrons are still employed, together with synchrotrons, for proton therapy while for carbon ion therapy synchrotrons have been till now the only option. The latest developments concern a superconducting cyclotron for carbon ion therapy, fast-cycling high frequency linacs and {\textquoteright}single room{\textquoteright} proton therapy facilities. These issues are discussed in the second part of the paper by underlining the present challenges, in particular the treatment of moving organs.", optnote="ISI:000280601700058", optnote="exported from refbase (https://references.ific.uv.es/refbase/show.php?record=401), last updated on Mon, 19 Dec 2011 12:02:31 +0000", issn="0168-9002", doi="10.1016/j.nima.2010.03.130", opturl="https://doi.org/10.1016/j.nima.2010.03.130", language="English" }